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Week three pick 'em analysis is being provided by colleague and soon to be contributor Don Harmon; a multiple league winner throughout his playing tenure. His picks are as follows:
- Kansas City over San Francisco
- Baltimore over Cleveland
- Dallas over Houston; look for a hungry Dallas team
- Minnesota over Detroit
- New England over Buffalo
- New Orleans over Atlanta
- New York Giants over Tennessee
- Pittsburgh over Tampa Bay
- Cincinnati over Carolina
- Philadelphia over Jacksonville
- Washington over St. Louis
- Denver over Indianapolis
- Arizona over Oakland
- Seattle over San Diego
- New York Jets over Miami
- Green Bay over Chicago